This study aims to produce a product of learning modules assisted wolfram mathematica tested validity and effectiveness to improve students' conceptual understanding. The type of research used is the development of research (development and development), with the selected development model is the 4D development model, which is defining, designing, developing, and deploying. The design stage will produce a draft of teaching materials evaluated based on material and media evaluations. Furthermore, the draft is tested on a small scale with 10 respondents who have received a course of differential equations, field trials have been conducted on the learning activities of differential equation in the class. The results of this study are: The result of the review of the material expert statement of the learning module is in the qualification is very feasible, that is equal to 4.17 or 83.33%. 2. The media expert responding to the learning module is in a very qualified qualification, that is 4.37 or 87.41%. Results of student responses that are at 4.11 or 82.13% are included in the qualification is very feasible. The developed modules are valid and feasible to be used in the learning process to facilitate the concept of mathematical concepts of learners. This teaching material is interesting and can learn from each other in the middle of minimal teaching materials and time in the classroom