The purpose of this research is to: (1) Knowing the development of learning media of mathematics nuanced Islamic Brain Gym on the material relation and function in SMA YP Unila. (2) To know the quality of learning media of Islamic mathematical monopoly with the help of Brain Gym which has been produced according to material experts, media experts, and religious experts. (3) Knowing the student's response to the Learning Mathematics Media of Islam-assisted Brain Gym developed. This research uses Research and Development method according to Borg and Gall with the procedure is limited to 7 stages of development are: Potential and Problems, Collecting information, Product Design, Design Validation, Design Improvement, Product Trial, and Product Revision, with data collection technique using interviews and questionnaires (questionnaires) in the form of Likert scale. data analysis techniques used are qualitative descriptive statistics. The result of this research is the learning media of mathematical monopoly of Islamic nuance using brain gym which is suitable to be used as instructional media which stated by: (1) media feasibility statement based on the material validation, media, and religion validation. (2) Interest in the use of monopoly games as learning media derived from the results of product testing in small groups, and field trials.